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Disturbances of primary hemostasis in patients with dilation cardiomyopathy

Sumarokov, A.B.; Buriachkovskaia, L.I.; Uchitel', I.A.; Shirokova, T.E.; Gupalo, E.M.; Gabrusenko, S.A.; Naumov, V.G.

Kardiologiia 49(9): 51-56

2009

ISSN/ISBN: 0022-9040
PMID: 19772503
Document Number: 629204
We studied morphological characteristics of platelets and parameters of platelet aggregation in patients with dilation cardiomyopathy. Augmented aggregatory activity of platelets was found in 76% of patients. In blood of majority of patients we found circulating leukocyte-platelet aggregates. This evidenced for development of inflammatory process and could be related to disturbances of blood rheology. In 2 patients examined by virusological method we revealed presence of a virus inside platelets. This phenomenon might serve as one of possible pathological pathways of disease progression at the account of spread of viral infection along vascular bed during thrombus formation.

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