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A case report of FOLFOX treatment for primary duodenal carcinoma with multiple liver metastases

Fujiwara, Y.; Naomoto, Y.; Tanabe, S.; Sakurama, K.; Noma, K.; Nishikawa, T.; Motoki, T.; Takaoka, M.; Shirakawa, Y.; Yamatsuji, T.; Matsuoka, J.; Tanaka, N.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 36(4): 655-657

2009

ISSN/ISBN: 0385-0684
PMID: 19381042
Document Number: 628624
We report a case of a woman in her sixties having primary duodenal carcinoma with multiple liver metastases who was treated with oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin(FOLFOX regimen). After completing 2 courses of the chemotherapy, computed tomography showed a partial response without any severe adverse events. Now at 8 months, the PR stage has been maintained. So far, no standard therapeutic strategy for metastatic duodenal carcinoma has been developed. However, we suggest a FOLFOX regimen can be highly effective as a safe approach for continuously maintaining the quality of life of patients with this rare type of cancer.

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