Histogenesis of infantile fibrosarcoma
Blizniukov, O.P.; Perevoshchikov, A.G.; Poliakov, V.G.
Arkhiv Patologii 71(1): 8-12
2009
ISSN/ISBN: 0004-1955 PMID: 19514351 Document Number: 628513
Eight cases of infantile deep soft tissue fibrosarcoma were examined. The tumor consists of neoplastic fibroblasts and myofibroblasts which differ from each other ultrastructurally. Well-differentiated collagen-forming neoplastic fibroblasts form one-half of infantile fibrosarcoma. Immunohistochemically and ultrastructurally immature embryonic-like fibroblasts were also identified. The latter closely resemble an embryonic perichondrial fibroblast of the embryonic limb during 6 weeks of development.