Polyomavirus-associated nephropathy: critical issues in virological monitoring
Cavallo, R.; Bergallo, M.; Sidoti, F.; Astegiano, S.; Terlizzi, M.E.; Costa, C.
New Microbiologica 32(3): 235-243
2009
ISSN/ISBN: 1121-7138 PMID: 19845105 Document Number: 628476
Polyomavirus-associated nephropathy is one of the most common viral complications in renal transplant recipients. Viral replication is the single common feature of all patients at risk of nephropathy. Therefore, screening for virus replication allows for the identification of patients at risk of developing nephropathy and permits earlier intervention, in particular a pre-emptive reduction of immunosuppression, with improvement of outcome. This paper describes the modes of virological monitoring and its role in the clinical management of renal transplant patients.