Nephrotic syndrome: new concepts in the pathophysiology of sodium retention
Zacchia, M.; Trepiccione, F.; Morelli, F.; Pani, A.; Capasso, G.
Journal of Nephrology 21(6): 836-842
2008
ISSN/ISBN: 1121-8428 PMID: 19034867 Document Number: 627818
The nephrotic syndrome is a frequent clinical condition characterized by fluid and salt retention. Although several theories have been put forward to explain the salt-retaining status, recent data have confirmed previous renal micropuncture observations indicating that the distal nephron is the site for increased salt reabsorption, eventually leading to sodium retention.