Systemic inflammatory reaction, antiendotoxin immunity and polyorgan insufficiency in patients of the intensive therapy departments
Potapov, A.L.
Klinichna Khirurhiia 2008(9): 54-56
2008
ISSN/ISBN: 0023-2130 PMID: 19278042 Document Number: 626353
The connection of C-reactive protein (CRP) and the antiendotoxin immunoglobulins (Ig) levels with lethality of the Intensive Therapy Department (DITH) patients was studied up. In 45 patients after hospitalization there were analyzed the levels of CRP, general and the specific antiendotoxin Ig. In 14 patients, who, suffering polyorgan insufficiency (POI), subsequently died, the CRP content was hightened and the antiendotoxins IgG concentration--reducted. The conclusion was formulated, that systemic inflammatory reaction and POI are connected with bacterial translocation phenomenon. Determination of CRP and the antiendotoxin IgG levels may be used for delineation of a group of the DITH patients owing high risk of POI occurrence and lethality.