Individual variability of cardiovascular reactivity during protective cardiac reflex in humans
Aftanas, L.I.; Brak, I.V.; Gilinskaia, O.M.; Sidorova, P.V.; Reva, N.V.; Makhnev, V.P.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 94(2): 163-175
2008
ISSN/ISBN: 0869-8139 PMID: 18516847 Document Number: 622283
Fail of fast recovering to normal state after aversive event is the key feature of individual intolerance to emotional stress. Within the framework of this idea, dynamics of the arterial blood pressure reactivity was studied studied using defensive reaction of the cardiac defense response elicited by strong aversive acoustic stimuli. Dynamical patterns of cardiovascular responses observed in this reaction makes made it possible to perform affective chronometry of defensive arousal. Healthy male volunteers with normal arterial blood pressure and patients with firstly diagnosed and untreated essential hypertension were studied. The beat-by-beat dynamics of blood pressure values were registered by means of finger-cuff Finapres technology. It was shown that among healthy individuals with normal resting blood pressure values hyperreactive persons with delayed late systolic and diastolic blood pressure increases ocurred. It was suggested that similiarity of delayed pressor effects ofhypereactive healthy individuals and those of hypertension patients incate a high risk of essential hypertension in highly reactive individuals.