Case of serious lidocaine intoxication
Takinami, Y.
Masui. Japanese Journal of Anesthesiology 57(4): 460-463
2008
ISSN/ISBN: 0021-4892 PMID: 18416205 Document Number: 620981
Lidocaine is frequently used as a local anesthetic and has very low incidence of serious complications. I report on a case of lidocaine intoxication in a 66-year-old man who presented with seizure and cardiac periarrest following the brachial plexus block with 450 mg of lidocaine. Twelve minutes after the lidocaine administration, he became unconscious and 29 minutes after, developed seizure. Bradycardia and subsequent cardiovascular depression were found 74 minutes after the lidocaine block. The patient was successfully treated with diazepam, atropine sulphate and transcutaneous pacing for each symptom, respectively.