Suggestions for prevention of adverse reactions after intravasal administration of iodinated contrast media
Kuefner, M.A.; Heinrich, M.; Bautz, W.; Uder, M.
Rontgenpraxis; Zeitschrift für Radiologische Technik 56(6): 199-206
2008
ISSN/ISBN: 0035-7820 PMID: 19294866 Document Number: 620299
Iodinated contrast media are widely used in computed tomography and angiography. Adverse reactions such as contrast-medium induced nephropathy (CIN), anaphylactoid reactions and iodine-induced thyrotoxicosis are associated with intravasal administration of contrast agents. Iodinated contrast agents are generally considered to be safe, but in rare cases they can cause severe life threatening situations. In this review we present an overview about the incidence, pathways, and risk factors of adverse reactions. Simple schemes including hydration protocols for prevention of CIN, medication for prophylaxis of iodine-induced thyrotoxicosis with thyreostatics and anaphylactoid reactions with histamine antagonists and corticosteroids are suggested.