Case report: severe, symptomatic hypomagnesemia in acute leptospirosis
Spichler, A.; Athanazio, D.A.; Furtado, J.; Seguro, A.; Vinetz, J.M.
American Journal of Tropical Medicine and Hygiene 79(6): 915-917
2008
ISSN/ISBN: 0002-9637 PMID: 19052304 Document Number: 620187
We report a case of severe hypomagnesemia in non-oliguric acute renal failure caused by leptospirosis that required large doses of magnesium replacement during the acute phase of disease. Biochemical studies confirmed kidney-related magnesium wasting and the mechanisms of this defect are discussed. Magnesium imbalance with its attendant clinical complications occurs in leptospirosis and should be monitored and treated aggressively in cases of leptospirosis-induced non-oliguric acute kidney injury.