Value of intraoperative fine-needle aspiration cytology and histopathologic biopsy in the diagnosis of pancreatic cancer
Zhao, D.-B.; Wang, Y.; Shan, Y.; Wang, C.-F.; Shao, Y.-F.; Zhao, P.
Zhonghua Zhong Liu Za Zhi 30(3): 231-233
2008
ISSN/ISBN: 0253-3766 PMID: 18756944 Document Number: 620122
To investigate the clinical value of intraoperative aspiration cytology and histopathologic biopsy in the diagnosis of pancreatic cancer. 142 patients with suspected pancreatic carcinoma underwent surgical exploration and the data were retrospectively analyzed. Chi-square test (chi2) was used to compare the accuracy between fine-needle aspiration cytology and histopathologic biopsy. Of the 192 patients with suspected pancreatic carcinoma, 80 were confirmed by histological biopsy and 87 by fine-needle aspiration cytology, with an accuracy rate of 83.8% and 93.1%, respectively. There was a statistically significant difference between these two groups (P = 0.027). No perioperative surgical complication was observed in this series. Intraoperative aspiration cytology and histopathologic biopsy was safe and helpful with a high accuracy for the diagnosis of pancreatic carcinoma.