Genotypes of hepatitis B virus in Henan Luohe area
Wang, F.-Q.; Huang, X.-L.; Li, A.-Q.; Wang, J.-G.; Zhang, F.-H.; Cui, Y.-B.; Yi, Y.; Chen, S.-Y.
Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 22(4): 257-259
2008
ISSN/ISBN: 1003-9279 PMID: 19105336 Document Number: 620115
To determine the main genotype of hepatitis B virus (HBV) prevailed in Henan Luohe area. Serum specimens were collected from 94 HBsAg positive individuals, and HBV S gene were obtained by PCR amplifying, and the gene sequences were analyzed and the polygenetic tree was drawn by the software MEGA3. About 75.7% samples of HBV S gene clustered in genotype C, about 20% samples clustered at genotype B in the HBV polygenetic tree, about 4.3% samples clustered at genotype D in the HBV polygenetic tree. The main genotype of hepatitis B virus prevalent in Henan Luohe is genotype C, genotype B is rarely seen, and genotype D is rarely seen.