Activity of indolicidin, alone or together with oxacillin, against Staphylococcus aureus and S. epidermidis
Walencka, E.; Sadowska, B.; Wieckowska-Szakiel, M.; Rózalska, B.
Medycyna Doswiadczalna i Mikrobiologia 60(3): 191-196
2008
ISSN/ISBN: 0025-8601 PMID: 19143172 Document Number: 618820
Difficulties in the treatment of staphylococcal infections as well as the increasing frequency of isolating resistant clinical strains have prompted a search, among the products of immune systems of plants and animals, for more effective antistaphylococcal therapies. This study examined the activity of indolicidin towards the planktonic cultures and biofilm of Staphylococcus aureus and S. epidermidis strains representing different clinical sources and various profiles of drug sensitivity. The synergistic effect between the peptide and oxacilin was also studied.