Orocecal transit time in patients with celiac disease from North India: a case control study
Rana, S.V.; Sharma, S.; Sinha, S.K.; Prasad, K.K.; Bhasin, D.K.; Singh, K.
Tropical Gastroenterology Official Journal of the Digestive Diseases Foundation 29(2): 98-100
2008
ISSN/ISBN: 0250-636X PMID: 18972770 Document Number: 618488
The mechanisms responsible for bowel disturbances in celiac disease are still unknown. Small bowel motor abnormalities may be involved in this pathological condition; however, there is no study addressing small bowel transit in patients of celiac disease from Northern India. The mouth-to-cecum transit time was studied in 80 celiac patients and 80 age and sex matched apparently healthy controls. Orocecal transit time in celiac patients was significantly delayed being 180+/-10.6 minutes (Mean+/-SE) as compared to 105+/-12.4 minutes in apparently healthy controls. This prolonged orocecal transit time could be due to impaired small bowel function (deranged motility) in patients with celiac disease.