Changes of airway obstruction parameters in healthy children caused by mother's smoking during pregnancy
Nosal, S.; Durdik, P.; Sutovska, M.; Franova, S.; Nosal, V.; Koppl, J.; Hamzik, J.; Banovcin, P.
Journal of Physiology and Pharmacology An Official Journal of the Polish Physiological Society 59 Suppl. 6: 523-529
2008
ISSN/ISBN: 0867-5910 PMID: 19218677 Document Number: 617993
The present study was aimed at the assessment of the impact of mother smoking during pregnancy on changes of phase angle (phi) and T(me)/T(E) index in healthy children. A hundred and twenty seven children, divided according to age (<6 months and >6 months of age) and mother smoking anamnesis were investigated by noncalibrated respiratory inductive plethysmography in the supine position. We found statistically significant changes of phi (p<0.05) and T(me)/T(E) in healthy children of non-smoking mothers against a group of smoking mother's children of up to 6 months of age. These differences were not confirmed in children older than 6 months. Moreover, in the smoking mother group, we found statistically significant changes (P<0.05) of phi and T(me)/T(E) in children of up to 6 months of age in comparison with children older than 6 month. The results revealed a negative impact of mother smoking during pregnancy represented by changes in airway obstruction parameters, which appeared especially in the group of youngest children.