Primary testicular lymphoma. Report of two cases and bibliographic review
Delgado Bavai, P.; Abad Roger, J.; Bono Ariño, A.; Esclarin Duny, M.; Marigil Gomez, M.; Sanz Velez, Jé.Ignacio.
Archivos Espanoles de Urologia 61(4): 527-531
2008
ISSN/ISBN: 0004-0614 PMID: 18592773 Document Number: 617789
We report two cases of primary testicular lymphoma and performed a bibliography review about this pathology. We describe two cases of primary testicular lymphoma in two male patients 69 and 61 yr. old respectively. In both cases, reason for consultation was increase of the right testicular size. After inguinal orchyectomy the diagnosis for the first case was large and medium T cell diffuse lymphoma, stage I (E)-A; three years after chemotherapy (R-CHOP) the patient is in complete remission. In the second case, the diagnosis was diffuse large B-cell lymphoma, and after receiving various chemotherapy regimens died 14 months after diagnosis. Testicular lymphoma is a very rare entity, despite being considered the most common testicular tumor in patients over the age of 60 years. Most of them are non-Hodgkin diffuse, intermediate or high grade of malignancy, B-cell immunophenotype, being T cell exceptional. Prognosis is poor due to their high tendency to systemic dissemination. The treatment is based on orchiectomy, chemotherapy and radiotherapy, although there is not a standardized regimen.