The combined treatment of colorectal cancer with liver metastases
Patiutko, I.I.; Poliakov, A.N.; Sagaĭdak, I.V.; Kotel'nikov, A.G.
Khirurgiia 7: 20-23
2008
ISSN/ISBN: 0023-1207 PMID: 18833159 Document Number: 617488
The direct and follow-up results of surgical and combined treatment of colorectal cancer with liver metastases are presented. Complication rate after liver resections was 28.4% and lethality was 3.5%. Follow-up results evidence the decrease of survival in patients with adjuvant chemotherapy after surgery. The safety of oxalyplatin in patients after liver resections, including its intraarterial infusion through the hepatic artery is shown. Oxalyplatin-based chemotherapy regimen tended to be more effective in comparison with 5-fluorouracil scheme, especially in patients with synchronous or multiple liver metastases. Considering that the difference is not statistically significant, further studies of oxalyplatin influence on survival of patients with colorectal liver metastases are necessary.