Investigation of the morphometric parameters of the visual cortical region (Field 17) in perinatal brain damage
Sal'kov, B.N.; Khudoerkov, R.M.
Arkhiv Patologii 70(4): 22-25
2008
ISSN/ISBN: 0004-1955 PMID: 18807522 Document Number: 617093
Autopsy brain specimens from babies who had experienced perinatal central nervous system damage and those who had shown no symptoms of brain lesion (a control group) were used to study the structural characteristics of Field 17 of the visual cortical region, by using computed morphometry. As compared with the control group, the children who had suffered from perinatal pathology showed no relationship between the increased width of a cortical plate diameter and the baby's age and Layers I and V had a significantly less width. In most cases Layers III, V and Layer VI + VII contained smaller neurons and the density of their arrangement was much less than in the brain of the control babies. It was concluded that the detected disorders suggest growth retardation and nonspecific structural and functional changes in the visual cortex in perinatal brain damage.