Chromatographic mass spectrometric assessment of the course of different forms of urolithiasis
Kadyrov, Z.A.; Suleĭmanov, S.I.; Istratov, V.G.; Kondakova, V.V.; Saakian, A.S.; Pirnazarov, M.; Nizomov, D.; Nusratulloev, I.
Klinicheskaia Laboratornaia Diagnostika 5: 14-17
2008
ISSN/ISBN: 0869-2084 PMID: 18590164 Document Number: 616986
The study has been undertaken to improve the methods for diagnosing urolithiasis, which comprehensively evaluate the severity of a pathological process and the results of treatment in patients with nephrolithiasis. The paper gives the data of investigating the processes of chromatographic mass spectrometric urinalysis in 82 patients aged 15 to 81 years urgently admitted to the units of urology of Moscow City Clinical Hospital Seven for a renal colic attack. The levels of lithogenic substances were measured in patients with different types of metabolic disturbances. There was evidence that the chromatographic mass spectrometric parameters of the level of lithogenic substances and hydrolytic enzymes might be used as diagnostic criteria for the progression of urolithiasis, the prediction of the severity of a pathological process, and the development of preventive methods against lithogenesis in patients with a renal colic attack.