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The state of peroxidation processes in the basal nuclei of the brain under conditions of an altered photoperiod

Sopova, I.I.; Zamoskiĭ, I.I.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 94(4): 371-379

2008

ISSN/ISBN: 0869-8139
PMID: 18666631
Document Number: 616265
The state ofperoxidation processes in the basal nuclei (the nucleus caudatus, globus pallidus, nucleus accumbens, amigdaloid complex) of the rat's brain under conditions of an altered photoperiod has been studied. A disturbance of regular photoperiodicity was shown to result in metabolic changes in the mentioned structures of the brain. Enhancement of the processes of lipid and protein peroxidation was observed in the basal nuclei under constant light, the intensity of fibrinolysis and proteolysis increases, the activity of the enzymes of antioxidant defense decreases. Heterodirectional changes of fibrinolysis and proteolysis in individual structures, a decrease of free radical processes against a background of accumulation of modified proteins were observed under conditions of constant darkness.

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