Cryosurgical ablation for aged patients with severe benign prostate hyperplasia: a report of 21 cases
Wang, A-xi.; Wang, D.; Tong, W.
Zhonghua Nan Ke Xue 13(5): 421-423
2007
ISSN/ISBN: 1009-3591 PMID: 17569258 Document Number: 615002
To study the clinical effect of cryosurgical ablation for aged patients with severe benign prostate hyperplasia. Twenty-one 72-91-year-old patients with severe benign prostate hyperplasia accompanied with cardiopulmonary dysfunction were treated by the ENDOCARE cryo-care surgery system with cryo-probes guided by type B ultrasound. Observations were made of the post-operation prostate biopsy and ultrasonogram as well as the changes of the urinary flow rate (UFR) and prostate-specific antigen (PSA). Degeneration and necrosis of the prostate tissues were found after the operation, with the signs of being completely melted. The mean UFRs before and after the operation were (3.8 +/- 2.1) ml/s and (17.0 +/- 5.8) ml/s, respectively (P < 0.01). Compared with the pre-operation level of PSA ([3.7 +/- 2.1] microg/L), the 1-week post-operation level was significantly higher ([22.6 +/- 13.1] microg/L) (P < 0.01), while the 4-week post-operation level significantly lower ([1.7 +/- 1.4] microg/L) (P < 0.05). Cryosurgical ablation, with satisfactory short-term curative effect, is a desirable option for the treatment of aged patients with severe benign prostate hyperplasia.