The dynamics of reparative regeneration of the rat skin nerve after various degree of its damage
Arkhipova, E.G.; Greten, A.G.; Krylov, V.N.
Morfologiia 131(3): 30-32
2007
ISSN/ISBN: 1026-3543 PMID: 17722569 Document Number: 614083
The dynamics of skin nerve regeneration was studied during 10-50 days after it was damaged by crushing in 163 outbred rats. Two series of experiments were conducted. In the first series, skin nerve (n. saphenus) was crushed by a hemostatic clamp in a region 2 mm long, while in second series it was crushed in a region of 4 mm length. The destructive processes in LIII and LIV spinal ganglia, the increase in the number of myelinated nerve fibers in the nerve region distal to the damaged area, the velocities of growth of damaged nerve fibers to the skin, were similar in both series during 10-50 days after the nerve was injured at different length. The velocity of myelination of regenerating nerve fibers in rats after 2 mm-long nerve injury was higher than that in animals after 4 mm-long nerve injury for a period of 30 days after the damage.