Validation of Polish version of CFQoL in patients with cystic fibrosis
Debska, G.; Mazurek, H.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 23(137): 340-343
2007
ISSN/ISBN: 1426-9686 PMID: 18361315 Document Number: 613802
Cystic Fibrosis Quality of Life Questionnaire (CFQoL), is a specific measurement tool of quality of life in adolescents and adults with cystic fibrosis, fully verified in English-speaking countries. However, introduction of new language version requires validation process. The aim of this study was to validate Polish version of CFQoL questionnaire. Language adaptation was performed after obtaining consent of the author. Healthy group (n=40, mean age = 19.5 +/- 3.4 years) assessed level of comprehension of each questionnaire item. Final Polish version of the questionnaire was assessed in 33 patients with cystic fibrosis (mean age = 21.8 +/- 3.4 years). The comparisons included CFQoL, SGRQ, WHOQOL-BREF, HADS and medical records analysis (spirometry, Shwachman-Kulczycki scale). CFQoL questionnaire was well understood and its graphics and time of completion were highly assessed. Good reliability of CFQoL was proven: Cronbach's Alpha coefficient was over 0.7 for all subscales, and high correlations between each item and general outcome for every subscale were found (r = from 0.63 to 0.93; p < 0.001). High correlation was observed in measurements repeated after 3 to 4 days (r = from 0.66 to 0.93; p < 0.001), the only difference between assessments was reduction of concerns about future (p = 0.007). Accuracy of the questionnaire was proven by significant correlations between CFQoL subscale assessing physical functioning and general outcome of SGRQ, psychosocial aspect of CFQoL and WHOQOL-BREF subscales, and emotional functioning subscale of CFQoL and anxiety and depression in HADS scale. There were no relationship between clinical data and CFQoL except Shwachman-Kulczycki scale. Polish version of the questionnaire fulfilled basic psychometric criteria and may be used for evaluation of quality of life of adolescents and adults with cystic fibrosis.