Diffusion weighted imaging: its diagnostic and differential value for prostate cancer
Shi, H.; Ding, H.-Y.
Zhonghua Nan Ke Xue 13(7): 605-609
2007
ISSN/ISBN: 1009-3591 PMID: 17725302 Document Number: 613495
To explore the diagnostic and differential value of diffusion weighted imaging (DWI) for prostate cancer. Included in the study were 50 patients with prostatic diseases, including 19 cases of prostate cancer (PCa) and 31 cases of benign prostatic hyperplasia (BPH), and another 16 healthy volunteers were recruited as controls. All underwent DWI sequence on a 1.5T superconducting MRI system with an endorectal coil. The results from DWIs and apparent diffusion coefficient (ADC) maps were treated statistically. The mean ADC value of the prostatic peripheral zone and the prostatic central gland of the 16 healthy volunteers were (170.23 +/- 37.39) x 10(-5) mm2/s and (127.84 +/- 17.93) x 10(-5) mm2/s, while those of the 31 BPH cases and 19 PCa cases were (175.21 +/- 64.86) x 10(-5) mm2/s and (104.23 +/- 26.15) x 10(-5) mm2/s, respectively. There were significant differences in the tissue types between any two groups after the treatment of one-way ANOVA, except between the groups of the peripheral zone and. BPH. PCa shows specific DWI features that could be distinguished from those of the normal prostatic tissues and BPH. Therefore, DWI has an important clinical application value in the diagnosis and differentiation of PCa.