Intrahepatic cholestasis of pregnancy: a disorder with increased fetal risks. Part II: fetal condition and medical management
Jóźwik, M.; Jóźwik, M.; Bartnicki, J.; Jóźwik, M.ł
Ginekologia Polska 78(5): 405-410
2007
ISSN/ISBN: 0017-0011 PMID: 17867335 Document Number: 613239
The aim of this review was to present recent information about the fetal condition in cases of intrahepatic cholestasis of pregnancy. A relatively mild course of maternal disease does not predict fetal well-being accurately. Increased risk of sudden intrauterine death was emphasized, implicating the need for more stringent obstetric monitoring of fetal condition in this disorder. A pathogenetic mechanism leading to sudden deterioration of fetal wellbeing was proposed and discussed. Current recommendations regarding medical management of intrahepatic cholestasis of pregnancy were also presented.