Prospective assessment of a training effect in correction of endothelial dysfunction and atherosclerosis risk factors in students (results of examination of Tomsk male students)
Kim, V.N.; Karpov, R.S.; Krivulina, G.B.; Shevelev, V.M.
Terapevticheskii Arkhiv 79(9): 30-33
2007
ISSN/ISBN: 0040-3660 PMID: 18038583 Document Number: 613068
To assess a training effect correcting endothelial dysfunction (ED), neurovegetative status and atherosclerosis risk factors (ARF) in male students. Ninety healthy students aged 18-25 years with ARF and ED were followed up after bicycle exercise (BE) 3 times a week: 30 males did BE for 1 month, 30--for 2 months and 30--for 3 months. Blood lipids, exercise tolerance (ET), parameters of cardiointervalography, dopplerangiography of the brachial artery and rheovasography of the forearm at rest and in tests with reactive hyperemia, hyperventilation were estimated immediately after, 1 and 3 months after BE. Two-month BE forms adequate structural trace the effect of which can be partially found 3 months later. Three-month BE tells on adaptation as it produces proatherogenic shifts in blood lipids. After the two-month cycle of BE positive effects regress in the following order: normalization of blood lipids, improvement of vegetovascular reactivity, high exercise tolerance and endothelium-related vasodilation. Two-month exercise is effective and safe, forms adaptive reserve of the body, structural effect of which partially persists for 3 months.