The morphofunctional state of the blood-brain barrier at the level of the medulla oblongata in experimental West Nile encephalitis

Pisarev, V.B.; Shmidt, M.V.; Petrov, V.A.

Voprosy Virusologii 52(4): 31-34

2007


ISSN/ISBN: 0507-4088
PMID: 17722608
Document Number: 610855
Pronounced clinical and morphological changes were found in the neurons and microcirculatory bed (MCB) vessels at the level of the medulla oblongata in experimental West Nile encephalitis (WNE). At the same time, the magnitude of changes in MCB vessels and nerve cells in the cores of the medulla oblongata correlated with the state of the surrounding astrocytic glia. It is suggested that the intensive astroglial reaction revealed during this experimental WNE reproduction promotes the prevention of neuronal lesion.

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