Research advance of microRNA and stem cell
Gao, J.; Yang, T.; Qiu, X.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 21(9): 1007-1010
2007
ISSN/ISBN: 1002-1892 PMID: 17933242 Document Number: 610322
To review the advance in the experimental studies of microRNA (miRNA) and the relationship between miRNA and stem cells. The related literature was reviewed, and the research findings of miRNA and stem cell were summarized. miRNA was non-coding small RNA (20-25 nt) involved in post-transcriptional change, that have been shown to regulate gene expressions. It has been reported that some kinds of miRNAs were likely important regulators for stem cells maintaining their state of self-renewal, and play key roles in their differentiation. miRNA as regulation of gene expressions, can be served as a new way for stem cells research.