Prognostic factors in typhoid ileal perforation: a prospective study of 53 cases
Edino, S.T.; Yakubu, A.A.; Mohammed, A.Z.; Abubakar, I.S.
Journal of the National Medical Association 99(9): 1042-1045
2007
ISSN/ISBN: 0027-9684 PMID: 17913115 Document Number: 610230
Background: Typhoid ileal perforation remains a serious complication of typhoid enteritis with high morbidity and mortality in many tropical countries.Aims and objectives: To determine the prognostic factors in typhoid perforation in Kano, Nigeria.Methodology: Fifty-three consecutive patients with typhoid perforation managed surgically were prospectively studied at the general surgical unit of Aminu Kano Teaching Hospital Kano, from March 2004 to February 2006.Results: There were 26 (49.1%) males and 27 (50.9%) females, with age range of 2-55 years and a mean +/- SD of 12.2 +/- 10.2 years. The morbidity was 49.1% and the most common postoperative complications included wound infection, wound dehiscence, burst abdomen, residual intra-abdominal abscesses and enterocutaneous fistula.Mortality was 15.1% and was significantly affected by multiple perforations, severe peritoneal contamination and burst abdomen (p value <0.05, odds ratio>1).The mean duration of hospital stay for survivors was 16.1 days with a range of 8-57 days.Conclusion: This study has attempted to determine the factors that statistically influence mortality in typhoid perforation in our environment.