Study of genetic diversity of nontypeable Haemophilus influenzae strains isolated from healthy children and patients with infection symptoms
Augustynowicz, E.; Szenborn, L.; Samet, A.; Sledzińska, A.; Gzyl, A.; Kielan, A.; Slusarczyk, J.
Medycyna Doswiadczalna i Mikrobiologia 59(2): 113-122
2007
ISSN/ISBN: 0025-8601 PMID: 17929409 Document Number: 609938
In the study the usefulness of genotyping methods for genetic variability examinations of non-typeable H. influenzae strains circulating in population as well as level the variability of NTHi strains isolated from healthy children and from symptomatic infection cases have been evaluated. Among genotyping methods evaluated, AFLP method of the MfeI/BglII set has been found most useful to study level of genetic variability of NTHi strains population. It has been shown that NTHi strains colonizing nasopharyngeal of healthy children present higher polymorphism level than strains isolated from patient with clinical symptoms of NTHi infection.