Genetic markers of predisposition to an aggressive course of chronic C hepatitis

Abdullaev, S.M.; Tselishcheva, I.I.; Samokhodskaia, L.M.; Kvasovka, V.V.; Ignatova, T.M.; Krasnova, T.N.; Bochkov, V.N.; Mukhin, N.A.; Abdullaev, S.M; Tselishcheva, I.I; Samokhodskaia, L.M; Kvasovka, V.V; Ignatova, T.M; Krasnova, T.N; Bochkov, V.N; Mukhin, N.A

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Genetic markers of predisposition to an aggressive course of chronic C hepatitis

Abdullaev, S.M.; Tselishcheva, I.I.; Samokhodskaia, L.M.; Kvasovka, V.V.; Ignatova, T.M.; Krasnova, T.N.; Bochkov, V.N.; Mukhin, N.A.

Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 2007(1): 8-13

2007

ISSN/ISBN: 0869-6047

PMID: 17338374

Document Number: 608867

The polymorphism of cytokine genes (11-1 beta, IL-10, IL-6, andTGF-beta 1) in patients with chronic C hepatitis and in healthy individuals was studied. The study found that the polymorphism of IL-10, IL-6, and TGF-beta 1 may at least partially explain the genetic predisposition to an aggressive course of the disease with the development of terminal stage.