Canine mastocytoma: report of 8 cases diagnosed by fine needle cytology and clinicopathologic correlations
Fulciniti, F.; Di Mattia, D.; Curcio, M.Pia.; Bove, P.; Rota, A.Maria.; Botti, G.
Acta Cytologica 51(4): 616-620
2007
ISSN/ISBN: 0001-5547 PMID: 17718137 Document Number: 608751
Background Mast cell proliferations are commoner in dogs than in humans; mass-forming lesions in the former are apt to fine needle sampling and the obtained cytopathological picture might he informing to enhance recognition of similar proliferations in humans.Case Clinical and cytopathologic data were collected from 8 cases of canine mastocytomas diagnosed by fine needle cytology. The cytopathologic presentation was correlated with the individual therapy performed and with the clinical stage. In all cases the cytopathological diagnosis was confirmed by histopathologic examination of the excised mass, by necropsy or by response to therapy.Conclusion There are marked similarities between canine and human mastocytomas, despite possible differences in the clinical course of the disease in both species. Canine mastocytomas may hence be used as an animal model of a human disease and, as such, familiarity with their cytologic presentation may be useful for recognizing mast cell proliferations in humans.