Hypertrophic pachymeningitis, glomerulonephritis and P-ANCA associated small vessel vasculitis
Mazzocchi, O.; Risso, J.A.; Viozzi, F.; Apa, N.P.; Peralba, M.C.; Nadal, M.A.; De Rosa, G.E.
Medicina 67(2): 151-155
2007
ISSN/ISBN: 0025-7680 PMID: 17593600 Document Number: 608010
Hypertrophic pachymeningitis is a very unusual disease, the main characteristic of which is thickening of the dura mater. We describe a patient who started this illness showing chronic headache and pauciimmune necrotizing extracapillary perinuclear antineutrophil cytoplasmic antibody (P-ANCA) associated glomerulonephritis. The diagnosis was made by brain magnetic resonance image. She received immunosuppressant therapy with prednisonel and cyclophosphamide with clinical improvement.