Reaction of epithelial cell rests of malassez to tooth emergence and occlusal function reaction of epithelial cell rests of Malassez to tooth emergence and occlusal function
Yu, X.-J.; Li, S.; Yu, L.; Xiao, C.-J.; Liu, Z.-X.
Hua Xi Kou Qiang Yi Xue Za Zhi 25(6): 599-602
2007
ISSN/ISBN: 1000-1182 PMID: 18306636 Document Number: 607016
OBJECTIVE To observe the morphology and proliferation of epithelial cell rests of Malassez (ECRM) during tooth emergence and occlusal function, and to evaluate its roles. Cytokeratin 14 (CK14) was applied as special marker of ECRM cells. The morphology and distribution of ECRM were examined by light and transmission electron microscopy. PV two-step immunohistochemical method was used to detect the expression of CK14 and proliferating cell nuclear antigen (PCNA) in ECRM. ECRM experienced instinct morphological changes during tooth emergence and occlusal function. They were observed as network of epithelial cells labeled by CK14, especially in furcation level regions of mouse molars and active cell proliferation during occlusion found period. Cell apoptosis was observed in many ECRM by transmission electron microscopy during late stage of the progess. ECRM may not only an accidental left-over of early embryonic development but rather play significant roles in occlusion found period.