Effect of small doses of interferon-alpha on food conditioning in young and ageing rats
Loseva, E.V.; Loginova, N.A.; Biriukovan, L.M.; Mats, V.N.; Pasikova, N.V.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 93(4): 386-393
2007
ISSN/ISBN: 0869-8139 PMID: 17654857 Document Number: 606924
The mechanisms of thermal regulation of skin blood flow during local heating to 35, 40 and 45 'C have been studied by the method of laser Doppler flowmetry in healthy volunteers. To estimate the state of microvascular bed the continuous wavelet-transform spectral analysis has been used. The amplitudes of fluxmotions in the range of blood flow active modulation significantly increase during local heating to 35 degrees C. The amplitudes of blood flow oscillations in the ranges of cardiorhythm and respiratory rhythm increase during local heating to 40 degrees C. The high amplitude oscillations in the range of myogenic activity are maintained. The amplitude of oscillations in the range of endothelial activity distinctly decreases and the oscillations in the range of neurogenic activity are inhibited. Local heating to 45 degrees C results in a significant decreasing of the oscillation amplitudes in the range of myogenic activity, and the amplitudes of cardio- and respiratory spectral components amount to their peak values among the temperatures of local heating under study.