Embryonic hepatic sarcoma in children: aspects of morphological diagnosis
Bliuznikov, O.P.; Shabanov, M.A.; Perevozchikov, A.G.
Arkhiv Patologii 69(1): 40-47
2007
ISSN/ISBN: 0004-1955 PMID: 19385134 Document Number: 606750
13 cases of embryonic undifferentiated sarcoma of the liver were examined. The tumor was detected in children: 50% being between 5-6 years of age and no sex domination was found. The tumors were solitary, large, well demarcated and had cystic areas of gelatinous degeneration. The tumor was composed of atypical round, stellate, spindle and epithelioid-like cells that were loosely arranged in a myxoid stroma. Entrapped bile ducts were commonly present. Electron microscopic and immunohistochemical findings showed no clear-cut differentiation of embryonic sarcoma cells.