A controlled clinical investigation of 3% diclofenac/2.5% sodium hyaluronate topical gel in the treatment of uncontrolled pain in chronic oral NSAID users with osteoarthritis
Roth, S.H.
International Journal of Tissue Reactions 17(4): 129-132
1995
ISSN/ISBN: 0250-0868 PMID: 8867642 Document Number: 6044
Topical application, 4 times daily for 2 weeks, of the diclofenac-hyaluronan gel to 59 osteoarthritis patients induced a significantly greater (p = 0.057) analgesic effect than placebo gel lacking the active substance applied to 60 control patients.
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