A case of bone involvement in hairy cell leukemia successfully treated with radiation therapy
Franco, P.; Filippi, A.Riccardo.; Fornari, A.; Marinone, C.; Ricardi, U.
Tumori 92(4): 366-369
2006
ISSN/ISBN: 0300-8916 PMID: 17036535 Document Number: 604252
We report the case of a 63-year-old man with a clearly established diagnosis of hairy cell leukemia, treated with multiple lines of chemotherapy, who complained of localized pain in the left humerus. Radiological findings showed a distrophic-blastic area within the humeral head. Fine-needle biopsy confirmed the hypothesis of bone involvement of hairy cell leukemia. The patient underwent radiotherapy at a dose of 25 Gy, obtaining a complete clinical response with resolution of pain and a partial recovery of the normal radiological structure of the humerus after 2 months. In addition to the case report, we present a short review of the literature focusing on the role of radiotherapy in this subset of patients.