Micro-focus X-ray for cochlear implantation research on small animals
Lu, W.; Xu, J.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 41(9): 702-704
2006
ISSN/ISBN: 1673-0860 PMID: 17111815 Document Number: 603051
To develop an imaging system suitable for cochlear implant research on small laboratory animals. A novel micro-focus X-ray imaging system was developed. The key features of the system were the use of a micro-focus X-ray source (less than 10 micrometers) and an appropriate choice of source-object and object-image distance. The new X-ray modality was evaluated on heads of cats, guinea pigs and rats. It proved to be an useful tool to provide excellent image of small animal cochlea, allowing a clear electrode position to be established, and also helped greatly in detecting the breakage of electrode array. Experimental studies performed in cats, guinea pigs and rats confirmed that micro-focus radiography was an important tool for cochlear implant research in laboratory