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Histopathological changes in liver, kidney and muscles of pesticides exposed malnourished and diabetic rats

Benjamin, N.; Kushwah, A.; Sharma, R.K.; Katiyar, A.K.

Indian Journal of Experimental Biology 44(3): 228-232

2006

ISSN/ISBN: 0019-5189
PMID: 16538862
Document Number: 602364
Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals. The examination revealed hepatotoxic, nephrotoxic and muscular necrotic effects in pesticides exposed rats. Toxicity was aggravated in protein-malnourished and diabetic animals and more so, if the animals were both diabetic and protein-malnourished.

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