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Reye's syndrome in a newborn infant

Papageorgiou, A.; Wiglesworth, F.W.; Schiff, D.; Stern, L.

Canadian Medical Association Journal 109(8): 717-720

1973

ISSN/ISBN: 0008-4409
PMID: 4746131
Document Number: 60233
A case of Reye's syndrome in a newborn infant, believed to be the first recorded in the perinatal period, is reported. The clinical, biochemical and histological findings are those previously recognized in older infants. The intractable acidosis, hypoglycemia and extreme degree of lactic acidosis reflect an advanced degree of hepatic involvement, probably initiated in utero, with resultant impairment of glycogenolysis and intermediary metabolism.

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Stern, L.; Wiglesworth, F.W. 1974: Reye's syndrome in a newborn Canadian Medical Association Journal 110(8): 886
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