Comparative assessment of the five-year results of surgical, combined, radiation and chemoradiotherapy in laryngeal cancer (T3N0M0)
Tkachëv, S.I.; Matiakin, E.G.; Liubaev, V.L.; Boĭkov, V.P.; Alieva, S.B.; Aliev, B.M.; Kondrat'eva, A.P.; Aketova, T.A.; Pirogova, N.A.; Loginova, I.N.
Voprosy Onkologii 52(4): 404-407
2006
ISSN/ISBN: 0507-3758 PMID: 17024811 Document Number: 602234
Four modalities of specific treatment for laryngeal cancer were compared in 158 patients. Five-year survival after chemoradiotherapy using cisplatin, 5-FU and bleomycin plus irradiation (65-70 Gy) was 87% versus 69.7; 66.2 and 45.9% after surgical, combined and radiotherapy, respectively. Chemoradiotherapy failed in 22.4%, as compared with 28.9; 31.5 and 41.7% after the alternative modalities, respectively. Organ preservation was used in 30.3% of surgical cases and 58%--in combined treatment group.