RAat (dermatological) Arriva/ProMetic
Brown, W.M.
Current Opinion in Molecular Therapeutics 8(1): 69-75
2006
ISSN/ISBN: 1464-8431 PMID: 16506528 Document Number: 601744
Arriva Pharmaceuticals Inc and ProMetic Life Sciences Inc are developing a gel formulation of recombinant alpha1-antitrypsin (rAAT). The therapy, as a topical formulation, is in phase II clinical trials for the potential treatment of atopic dermatitis and severe dermatological disorders. rAAT is also under preclinical investigation for the potential treatment of other inflammatory skin conditions, including psoriasis, as well as for otitis media.