Prevention trials in Alzheimer disease: one step forward?
Touchon, J.; Portet, F.; Gauthier, S.
Neurology 67(9 Suppl 3): S21-S22
2006
ISSN/ISBN: 0028-3878 PMID: 17101931 Document Number: 601513
Finding strategies that prevent or delay the onset of dementia in Alzheimer disease (AD) will be a challenge for the years to come. Prevention trials in AD pose several unresolved questions, including methodologic, scientific, medical, regulatory, and ethical issues. A critical concern is the benefit and relative risk of giving a treatment to non-demented patients or to asymptomatic subjects. Some trials are under way and will perhaps move the field of prevention of dementia one big step forward.