The degree of coronary artery calcinosis as a prognostic factor of asymptomatic cardiovascular complications: results of meta-analysis
Sinitsyn, V.E.; Voronov, D.A.; Morozov, S.P.
Terapevticheskii Arkhiv 78(9): 22-27
2006
ISSN/ISBN: 0040-3660 PMID: 17076220 Document Number: 601190
Aim. To investigate prognostic implications of the calcium index estimated tomogrophycally for identification of patients at high risk to develop cardiovascular complications (non-fatal myocardial infarction, lethal coronary hear disease, coronary revascularization) in the absence of clinical manifestations.Material and methods. Meta-analysis of the results of studies on prognostic implications of coronary arteries calcinosis was made with standardized risk ratio as a metameter. The meta-analysis included tests for systemic error related to publishing primarily positive results and data heterogenicity.Results. Overall risk ratios for cardiovascular complications ranged from 2.1 to 9.3 for different degrees of coronary artery calcinosis.Conclusion. Calcium index is an independent risk factor of complications of cardiovascular diseases.