Is there a role for cytokine based therapies in fibromyalgia
Wallace, D.J.
Current Pharmaceutical Design 12(1): 17-22
2006
ISSN/ISBN: 1381-6128 PMID: 16454720 Document Number: 600727
Cytokines are glycoproteins that serve as chemical messengers between cells. They assist in the regulation of cell growth and repair and also have immune modulating properties. Cytokines play a role in diverse clinical processes and phenomena such as fatigue, fever, sleep, pain, stress and aching. A review of the fibromyalgia literature and related studies suggest that IL-1, IL-6 and IL-8 are dysregulated in the syndrome. Therapies directed against these cytokines may be of potential importance in the management of fibromyalgia.