Clinical research of primary intraspinal hemangiopericytoma
Zhao, Y.; Zhao, P.; Zhao, J.-z.
Zhonghua Yi Xue Za Zhi 86(7): 453-456
2006
ISSN/ISBN: 0376-2491 PMID: 16677570 Document Number: 600398
To investigate the effective means of treatment for primary intraspinal hemangiopericytoma. The clinical presentation, imaging features, treatment and prognosis of 23 cases of intraspinal hemangiopericytoma, 14 males and 9 females, aged 39.1 (14 - 65), were analyzed retrospectively. Subtotal resection was performed on 11 cases, subtotal resection and radiotherapy on 4 cases, total resection on 5 cases, and total resection and radiotherapy on 3 cases. Spinal stabilization was conducted on 2 cases after total resection with severe damage of the vertebral body or pedicle of vertebral arch. Nineteen cases were followed up for 3.8 years (6 months-10 years). The recurrence rate was 68% and the metastasis rate was 21%. Primary intraspinal hemangiopericytoma should be resected en bloc with neighboring dura mater to reduce blood loss and recurrence. Resection of large lesions may be safer after preoperative embolization. The patients undergoing subtotal resection need adjuvant radiotherapy. The patients with evident spinal involvement may benefit from spinal stabilization. Lesions arising from dural mater have better prognosis. Postoperative long-term follow-up is necessary.