Comparison between genes of Alzheimer's disease and brain tissue of others
Gaszner, P.ét.; Havas, L.ás.ó
Neuropsychopharmacologia Hungarica a Magyar Pszichofarmakologiai Egyesulet Lapja 8(4): 211-214
2006
ISSN/ISBN: 1419-8711 PMID: 17575621 Document Number: 600191
We have examined samples from 14 donors that were prepared from 44 different anatomical regions of the brain. These samples were prepared both as frozen formalin-fixed, paraffin embedded. There were 310 frozen samples and 367 fixed samples. A total of 265 of the frozen samples were tested for RNA quality. A very high quality was obtained with 122 of these frozen samples (44%). The sample numbers were not large enough to draw conclusions about RNA quality for individual brain regions. Silver staining was performed on some samples and 5 of 7 samples tested from one donor diagnosed with Alzheimer's like dementia showed evidence of Alzheimer's disease by this method.