Skin neuroendocrine carcinoma metastasis: a case report
Rossitto, M.; Fedele, F.; Pantè, S.; Crescenti, F.; Incardona, S.; Ciccolo, A.; Famulari, C.
Annali Italiani di Chirurgia 77(1): 69-73
2006
ISSN/ISBN: 0003-469X PMID: 16910364 Document Number: 599889
Merkel cell carcinoma (MCC) is a rare and aggressive skin tumour with a highly malignant nature whose appropriate treatment is still debated. The Authors report a case of cutaneous metastasis from neuroendocrine carcinoma and analyse new diagnostic and therapeutic options of neoplasms that occurs in sun-exposed areas. The authors present the clinical, immunocytochemical characteristic of primary and secondary skin localization of a neuroendocrine tumor that affected a woman. Histological and immunocytochemical analysis demonstrated that the secondary cutaneous localization appeared to be compared to the primary tumour. The case confirm the high incidence of regional metastasis; a wide surgical excision of tumor and regional lymphadenectomy is therefore recommended for primary treatment of MCC; the radiation treatment minimized the local recidives with long time survival.