Effect of truncal adiposity on plasma lipid and lipoprotein concentrations
Niederauer, C.M.; Binkley, T.L.; Specker, B.L.
Journal of Nutrition Health and Aging 10(2): 154-160
2006
ISSN/ISBN: 1279-7707 PMID: 16554953 Document Number: 598820
Objective: The purpose of this study was to determine the effect of body fat distribution on plasma lipid and lipoprotein concentrations in healthy individuals. Methods: Subjects were 290 women and 223 men aged 20-66 years old. Lipid panels were obtained and truncal adiposity measurements were determined by total body dual energy x-ray absorptiometry (DXA). Physical activity was measured using a modification of the Seven Day Physical Activity Recall Questionnaire and dietary intake was collected by 24-hour recall. General linear models were used with covariates included. Results: Percent of total body fat in the trunk had the strongest correlation to the android/gynoid regional fat mass ratio determined by regional DXA analyses in both women (r2=0.97, p<0.001) and men (r2=0.93, p<0.001). Total cholesterol (r=0.134, p<0.05), LDL (r=0.140, p<0.05), HDL (r=-0.181, p<0.001), total cholesterol to HDL ratio (r=0.240, p<0.001) and triglyceride (r=0.300, p<0.001) concentrations had the strongest correlation to percent of total body fat in the trunk in women. Total cholesterol (r=0.151, p<0.05), total cholesterol to HDL ratio (r=0.216, p<0.001), and triglyceride (r=0.227, p<0.001) concentrations had the strongest correlation to percent of total body fat located in the trunk among men. Conclusion: Lipid profiles, consistent with increased cardiovascular risk, were associated with percent of total body fat in the trunk independent of lifestyle factors.